대사증후군 연구실

Research Interests: Obesity, NAFLD, Liver Fibrosis, Type 2 Diabetes, Sweet sweetened beverages and gut, Disrupted circadian rhythm

PI and Researchers

PI
- 조은희 (Eun-Hee Cho, M.D., Ph.D. ehcho@kangwon.ac.kr,)
- Dr. Cho is a Professor and Head of the Department of Endocrinology and Metabolism. She is a member of the Korean Diabetes Association as well as the Korean Endocrinology Society. Dr. Cho's research centers around identifying molecular candidates involved in energy metabolism, inflammation, and fibrosis, which mediate the health benefits of liver fibrosis such as metformin, FGF-21, resveratrol or GPR91 antagonists. In particular, her primary focus is to find out the key fibrogenic signaling pathways that prevent or delay progress in liver fibrosis using state-of-the-art molecular techniques and cell bioenergetics tools in cells and animal models.
Researchers
- Dr. Seon Mi Kang, M.D., Ph.D, Department of Endocrinology and Metabolism, School of medicine, KNU
- Dr. Dae-Hee Choi, M.D., Ph.D. Department of Gastroenterology, School of medicine, KNU

Research Summary

1. Obesity, NAFLD, and Liver fibrosis
- We study molecular mechanisms of inflammation, fibrogenesis, and lipid/cholesterol metabolism in the pathogenesis of obesity, non-alcoholic fatty liver disease, and liver disease. Our specific research interest is to define how hepatic stellace cells and macrophages play crucial roles in disease development of liver fibrosis and how candidate medical components/natural products impact fibrogenic or inflammatory pathways to prevent the progress of liver fibrosis.

Research